What is transient aplastic crisis?

What is transient aplastic crisis?

Transient aplastic crisis (TAC) is a temporary cessation of red cell production by the bone marrow leading to severe anemia, most commonly seen in patients predisposed to increased RBC destruction.

What are the two types of aplastic anemia?

There are two different types: Acquired aplastic anemia. Inherited aplastic anemia.

What is aplasia medical term?

Aplasia is a condition in which an organ, limb, or other body part does not develop. In most cases, aplasia is obvious at birth.

Is aplastic anemia the same as pancytopenia?

“Aplastic Anemia” is not really only an “anemia,” but instead it is a pancytopenia in which leukopenia, anemia, and thrombocytopenia are almost always found. This disease comprises a total bone marrow failure where stem cells are unable to generate all mature elements.

What causes aplastic crisis in sickle cell disease (SCD)?

Parvovirus B19 infection causes transient aplastic crisis in sickle cell disease (SCD) due to a temporary interruption in the red blood cell production. Toxicity from hydroxyurea includes anemia and reticulocytopenia, both of which also occur during a transient aplastic crisis event.

What is aplastic anemia disease?

Aplastic anemia is an autoimmune disease in which the body fails to produce blood cells in sufficient numbers. Blood cells are produced in the bone marrow by stem cells that reside there. Aplastic anaemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets.

What does aplastic anemia mean?

Medical Definition of aplastic anemia. : severe anemia that results from defective functioning of the bone marrow with an abnormal reduction in blood cells and that is characterized especially by headache, fatigue, paleness, fever, recurrent infections, bruising or rashes, and rapid or irregular heartbeat.