How can Niddm be treated?

How can Niddm be treated?

Oral drugs for the treatment of NIDDM include sulphonylurea derivatives used in first-line treatment in patients who are not grossly obese, metformin, which is often the treatment of choice for obese patients and, more recently, the alpha-glucosidase inhibitors, such as acarbose, which are effective in reducing the …

What is the best treatment for nephropathy?

Medications to treat IgA nephropathy include:

• High blood pressure medications. Taking angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) can lower your blood pressure and reduce protein loss.
• Omega-3 fatty acids.
• Immunosuppressants.
• Statin therapy.
• Diuretics.

What is the first line drug for patients with type 2 diabetes and obesity?

Metformin is indicated as the first line agent for obese patients with diabetes, and although metformin is considered to have weight neutral effects, some studies have shown weight loss of up to 2–3 kg [24,25].

Does Type 2 diabetes increase uric acid?

On the other hand, people with type 2 diabetes often have high levels of uric acid in their blood, which could be due to extra fat. If you’re overweight, your body creates more insulin. That makes it harder for your kidneys get rid of uric acid, which may lead to gout.

What causes NIDDM?

Non-insulin-dependent diabetes mellitus (NIDDM) results from an imbalance be- tween insulin sensitivity and insulin secretion. Both longitudinal and cross-sectional studies have demonstrated that the earliest detectable abnormality in NIDDM is an impairment in the body’s ability to respond to insulin.

What are dapagliflozin tablets?

Dapagliflozin is a medicine is mainly used to treat type 2 diabetes. Sometimes it can be used together with insulin to treat type 1 diabetes. Dapagliflozin is usually prescribed for type 2 diabetes if you cannot take metformin.

How do you treat diabetic nephropathy naturally?

Tips for healthy kidneys

1. Keep your blood sugar levels within their target range.
2. Manage your blood pressure and get treatment for high blood pressure.
3. If you smoke, quit.
4. Lose weight if you’re overweight or obese.
5. Maintain a healthy diet that’s low in sodium.
6. Make exercise a regular part of your routine.

What is the first-line treatment for T2DM?

In most international guidelines on the management of hyperglycaemia, metformin is the recommended first-line glucose-lowering agent in patients with type 2 diabetes.

What is the initial treatment for type 2 diabetes?

Metformin (Fortamet, Glumetza, others) is generally the first medication prescribed for type 2 diabetes. It works primarily by lowering glucose production in the liver and improving your body’s sensitivity to insulin so that your body uses insulin more effectively.

Does metformin increase uric acid?

Diabetic patients showed a significant increase in serum uric acid, fasting blood sugar, glycated hemoglobin, and body mass index when compared to control subjects. The serum uric acid levels of metformin and glibenclamide taking groups were significantly higher than the control group.

Can allopurinol lower blood sugar?

4 Discussion. Based on several biological and clinical observations, recent studies suggest that allopurinol use may be associated with improved insulin sensitivity and blood glucose levels.

What are the new guidelines for the treatment of gout?

New Gout Management Guidelines: A Quick and Easy Guide. Data also support the efficacy of COX-2 inhibitors; the TFP also recommends celecoxib (an initial dose of 800 mg, followed by 400 mg on day 1, and then dosed at 400 mg twice daily for 1 week) for acute disease in patients intolerant to or with contraindications to other NSAIDs.

Which is the first line treatment for NIDDM?

Oral drug therapies used in NIDDM include sulphonylurea derivatives, which are a first-line treatment in patients who are not grossly obese, metformin, which is the treatment of choice for obese patients, and alpha-glucosidase inhibitors such as acarbose, which are used mainly to reduce postprandial blood glucose peaks.

How are NSAIDs used to treat gout and pseudogout?

Indomethacin has been the NSAID traditionally used to treat acute inflammation in gout, though other NSAIDs are effective in this setting as well. Like all NSAIDs, indomethacin blocks cyclooxygenase and thereby reduces the generation of prostaglandins. Unlike most NSAIDs, which inhibit both COX-1 and COX-2,…

Which is better for gout topical ice or colchicine?

Given similar efficacy and a lower risk of adverse effects, low-dose colchicine over high-dose colchicine is strongly recommended when colchicine is the chosen agent. Using topical ice as an adjuvant treatment over no adjuvant treatment is conditionally recommended for patients experiencing a gout flare.